Description

(n-tert-Butoxycarbonyl-n-[(1'R)-Hydroxy-1-Phenyl)Ethyl])-4-Aminophenylethylamine is a sophisticated chiral amine derivative and a key building block in advanced organic synthesis. Its value lies in its dual functional groups—a protected amine (Boc) and a chiral benzylic alcohol—which enable precise stereochemical control in the construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical industry, particularly for developing active pharmaceutical ingredients (APIs) and chiral ligands for asymmetric catalysis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of chiral drug candidates, especially for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Catalyst Ligand Synthesis: Used to construct chiral ligands for transition metal catalysts in enantioselective reactions.
• Peptidomimetic Research: Serves as a building block for creating non-natural amino acids and peptide analogs with enhanced stability and bioactivity.
• Chemical Biology Probes: Employed in the development of molecular probes and tools for studying biological pathways and protein interactions.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for high-value, low-volume specialty chemicals.

Basic Information

Product Name	(n-tert-Butoxycarbonyl-n-[(1'R)-Hydroxy-1-Phenyl)Ethyl])-4-Aminophenylethylamine
CAS No.	223673-36-7
Molecular Formula	C21H28N2O3
Molecular Weight	356.46 g/mol
Synonyms	N-Boc-N-[(1R)-1-Hydroxy-1-phenylethyl]-4-(2-aminoethyl)aniline; (R)-N-(tert-Butoxycarbonyl)-N-(1-hydroxy-1-phenylethyl)-4-(2-aminoethyl)aniline; 4-[2-[[(1R)-1-Hydroxy-1-phenylethyl](tert-butoxycarbonyl)amino]ethyl]aniline; Boc-protected chiral amino alcohol derivative; (1R)-1-Phenyl-1-[N-(tert-butoxycarbonyl)-4-(2-aminoethyl)anilino]ethanol
EINECS	Contact for details

Quality Control

Our (n-tert-Butoxycarbonyl-n-[(1'R)-Hydroxy-1-Phenyl)Ethyl])-4-Aminophenylethylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive; prolonged exposure to light should be avoided to prevent decomposition. Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.