Description

1-Pyrrolidinepropanenitrile,α-Ethylidene-,(Alphae)-(9Ci) is a specialized organic compound featuring a pyrrolidine ring and a nitrile functional group, identified by CAS number 223129-23-5. This high-purity intermediate is valued for its unique molecular scaffold, which is critical for constructing complex pharmacologically active molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for use in advanced synthetic routes and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its nitrile moiety for biological activity.
• Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds and fine chemicals in process development.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Investigated as a monomer or functional additive in the development of specialty polymers and advanced materials.

Basic Information

Item	Detail
Product Name	1-Pyrrolidinepropanenitrile,α-Ethylidene-,(Alphae)-(9Ci)
CAS No.	223129-23-5
Molecular Formula	C9H14N2
Molecular Weight	150.22 g/mol
Synonyms	α-Ethylidene-1-pyrrolidinepropanenitrile; (αE)-α-Ethylidene-1-pyrrolidinepropanenitrile; 2-(1-Pyrrolidinyl)-2-butenenitrile; 2-Butenenitrile, 2-(1-pyrrolidinyl)-; 2-(Pyrrolidin-1-yl)but-2-enenitrile; (E)-2-(Pyrrolidin-1-yl)but-2-enenitrile; (αE)-α-Ethylidene-1-pyrrolidinepropanenitrile (9CI)
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinepropanenitrile,α-Ethylidene-,(Alphae)-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This compound may be moisture-sensitive; ensure containers are sealed under an inert atmosphere if specified for the grade.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.