Description

4'-(Boc-Amino)-Biphenyl-4-Carboxylic Acid is a high-purity, protected amino acid derivative widely used as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile and stable intermediate for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and targeted therapy research.
• Peptidomimetics & PROTACs: Used in the construction of peptide-like molecules and Proteolysis-Targeting Chimeras (PROTACs) for drug discovery.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalyst and material science.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and protein function.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, and plant growth regulators.
• Advanced Material Synthesis: Used in the creation of organic semiconductors, liquid crystals, and polymers with specific functional properties.

Basic Information

Product Name	4'-(Boc-Amino)-Biphenyl-4-Carboxylic Acid
CAS No.	222986-59-6
Molecular Formula	C18H19NO4
Molecular Weight	313.35 g/mol
Synonyms	4'-(tert-Butoxycarbonylamino)-[1,1'-biphenyl]-4-carboxylic Acid; 4'-[(tert-Butoxycarbonyl)amino]biphenyl-4-carboxylic Acid; 4'-Boc-Aminobiphenyl-4-carboxylic Acid; BOC-Aminobiphenylcarboxylic Acid; 4-Carboxy-4'-Boc-aminobiphenyl; N-Boc-4'-Aminobiphenyl-4-carboxylic Acid; [1,1'-Biphenyl]-4-carboxylic acid, 4'-[[(1,1-dimethylethoxy)carbonyl]amino]-
EINECS	Contact for details

Quality Control

Our 4'-(Boc-Amino)-Biphenyl-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.