Description

2-Aziridinecarboxylicacid,(1-Methylethylidene)Hydrazide,(2S)-(9Ci) is a specialized chiral aziridine derivative, a high-value building block in advanced organic synthesis. Its unique structure, featuring a protected hydrazide and a stereogenic center, makes it a critical precursor for constructing complex nitrogen-containing heterocycles and chiral ligands. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly those targeting neurological disorders and cancers.
• Agrochemical Research: Used in the development of new pesticides and herbicides with specific chiral activity.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands used in asymmetric hydrogenation and other catalytic processes.
• Peptidomimetic Chemistry: Employed in the design and synthesis of peptidomimetics and constrained amino acid analogs for medicinal chemistry.
• Polymer Modification: Can be used to introduce reactive aziridine functionality into polymers for cross-linking or creating specialty materials.
• Academic & Institutional R&D: A valuable reagent for methodological studies in organic synthesis and heterocyclic chemistry at universities and research institutes.

Basic Information

Product Name	2-Aziridinecarboxylicacid,(1-Methylethylidene)Hydrazide,(2S)-(9Ci)
CAS No.	222557-18-8
Molecular Formula	C7H13N3O
Molecular Weight	155.20 g/mol
Synonyms	(2S)-2-Aziridinecarboxylic acid (1-methylethylidene)hydrazide; (S)-2-Aziridinecarboxylic acid isopropylidenehydrazide; (S)-1-(2-Aziridinylcarbonyl)-2-(propan-2-ylidene)hydrazine; (2S)-1-(Propan-2-ylidene)-2-(2-aziridinylcarbonyl)hydrazine; (S)-Acetone aziridine-2-carboxyl hydrazone; Aziridine-2-carboxylic acid, (1-methylethylidene)hydrazide, (2S)-; (2S)-2-Carboxyaziridine acetone hydrazone
EINECS	Contact for details

Quality Control

Our 2-Aziridinecarboxylicacid,(1-Methylethylidene)Hydrazide,(2S)-(9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high chiral purity and chemical integrity, meeting the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.