Description

trans-Methyl 3-Aminocyclopentanecarboxylate Hydrochloride is a high-purity, pharmaceutically relevant chiral building block and intermediate. This compound is critical for the synthesis of complex molecules, offering a defined stereochemical center essential for developing active pharmaceutical ingredients (APIs) with specific biological activity. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry influences biological efficacy.
• Peptidomimetics & Bioactive Molecule Construction: Serves as a constrained, cyclic amino acid derivative for designing enzyme inhibitors and receptor modulators.
• Asymmetric Catalysis Research: Employed as a ligand precursor or a test substrate in the development of new chiral catalysts.
• Custom Synthesis & Contract Manufacturing: A starting material for custom chemical synthesis services catering to R&D and pilot-scale production.
• Academic & Industrial R&D: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	trans-Methyl 3-Aminocyclopentanecarboxylate Hydrochloride
CAS No.	222530-45-2
Molecular Formula	C7H14ClNO2
Molecular Weight	179.65 g/mol
Synonyms	Methyl (1R,3S)-3-aminocyclopentanecarboxylate hydrochloride; (1R,3S)-3-Aminocyclopentanecarboxylic acid methyl ester hydrochloride; trans-3-Amino-1-cyclopentanecarboxylic acid methyl ester HCl; Methyl trans-3-aminocyclopentanecarboxylate HCl; (1R,3S)-3-Aminocyclopentane-1-carboxylic acid methyl ester hydrochloride; Cyclopentanecarboxylic acid, 3-amino-, methyl ester, hydrochloride, (1R,3S)-rel-; 3-Aminocyclopentanecarboxylic acid methyl ester hydrochloride (trans isomer)
EINECS	Contact for details

Quality Control

Our trans-Methyl 3-Aminocyclopentanecarboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.