Description

3,5-Diiodobenzeneacetic acid is a high-purity, multi-functional aromatic building block characterized by its two iodine substituents, which provide unique reactivity for advanced coupling reactions. This compound is critical for research and development in pharmaceutical chemistry, serving as a versatile intermediate for creating complex molecular architectures. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce halogenated motifs or construct novel heterocyclic systems.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for thyroid hormone analogs and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides where the diiodo-substituted benzene core imparts specific biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl structures.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.
• R&D for Diagnostic Agents: Investigated as a precursor for radioiodination or in the development of contrast agents and diagnostic probes.

Basic Information

Product Name	3,5-Diiodobenzeneacetic acid
CAS No.	221700-19-2
Molecular Formula	C8H6I2O2
Molecular Weight	403.94 g/mol
Synonyms	(3,5-Diiodophenyl)acetic acid; 2-(3,5-Diiodophenyl)acetic acid; 3,5-Diiodobenzeneacetic Acid; NSC 404058; 3,5-Diiodohomophenylacetic acid; Diiodobenzeneacetic acid; α-(3,5-Diiodophenyl)acetic acid
EINECS	Contact for details

Quality Control

Our 3,5-Diiodobenzeneacetic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.