Description

4-Chloro-6,7-dimethoxy-2-phenylquinazoline is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline class of heterocyclic compounds. This compound is of significant commercial interest for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries engaged in the development of novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of tyrosine kinase inhibitors and other targeted cancer therapies.
• Agrochemical Research: Serves as a core scaffold for developing new herbicides and fungicides with specific modes of action.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex quinazoline-based molecular libraries for drug discovery.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in API manufacturing.
• Material Science Research: Investigated for potential applications in creating organic electronic materials due to its conjugated structure.

Basic Information

Product Name	4-Chloro-6,7-Dimethoxy-2-Phenylquinazoline
CAS No.	221697-86-5
Molecular Formula	C₁₇H₁₅ClN₂O₂
Molecular Weight	314.77 g/mol
Synonyms	4-Chloro-6,7-dimethoxy-2-phenylquinazoline; 2-Phenyl-4-chloro-6,7-dimethoxyquinazoline; 4-Chloro-2-phenyl-6,7-dimethoxyquinazoline; 6,7-Dimethoxy-2-phenyl-4-chloroquinazoline; Quinazoline, 4-chloro-6,7-dimethoxy-2-phenyl-; 221697-86-5; 4-Chloro-6,7-bis(methoxy)-2-phenylquinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-6,7-dimethoxy-2-phenylquinazoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.