Description

5-Bromo-1,1,3,3-Tetramethylisoindoline is a specialized organic compound belonging to the isoindoline class, characterized by its brominated and tetramethyl-substituted structure. This chemical serves as a valuable synthetic intermediate and building block in advanced organic synthesis and materials science. It is particularly relevant for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity, functionalized heterocycles for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways, where the isoindoline scaffold is pharmacologically relevant.
• Agrochemical Synthesis: Serves as a key precursor in the development of new pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials or host materials in OLED displays and lighting due to its rigid, substituted aromatic structure.
• Coordination Chemistry & Catalysis: Utilized to synthesize novel ligands for metal complexes in catalytic applications and materials science.
• Polymer & Material Science: Incorporated into polymers to modify thermal stability, optical properties, or to create functionalized surfaces.
• Academic & Industrial R&D: Essential for research in synthetic methodology development and exploring new chemical entities across multiple disciplines.

Basic Information

Product Name	5-Bromo-1,1,3,3-Tetramethylisoindoline
CAS No.	221368-74-7
Molecular Formula	C12H16BrN
Molecular Weight	254.17 g/mol
Synonyms	5-Bromo-1,1,3,3-tetramethyl-2,3-dihydro-1H-isoindole; 1,1,3,3-Tetramethyl-5-bromoisoindoline; 5-Bromotetramethylisoindoline; 2,3-Dihydro-5-bromo-1,1,3,3-tetramethyl-1H-isoindole; 5-Bromo-1,1,3,3-tetramethylisoindole; 5-Bromo-TMIO
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,1,3,3-Tetramethylisoindoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.