Description

Boc-D-Allylglycine Dcha Salt is a protected, non-proteinogenic amino acid derivative widely used in advanced peptide synthesis and medicinal chemistry research. This high-purity building block is critical for introducing unique structural motifs and side-chain functionalities into target molecules. It is primarily utilized by pharmaceutical R&D teams, CROs, and fine chemical manufacturers developing novel therapeutic peptides and bioactive compounds.

Application

• Peptide Synthesis: A key chiral building block for the solid-phase and solution-phase synthesis of complex peptides, enabling the incorporation of the D-allylglycine residue.
• Medicinal Chemistry & Drug Discovery: Used in the research and development of new drug candidates, particularly for creating peptide-based therapeutics and enzyme inhibitors.
• Bioconjugation & Chemical Biology: The allyl side chain provides a handle for further chemical modification via click chemistry (e.g., thiol-ene reactions) for labeling or linker attachment.
• Production of Custom Amino Acids: Serves as a precursor for the synthesis of other specialized, non-natural amino acids after deprotection and further functionalization.
• Academic & Industrial Research: Employed in studying enzyme mechanisms, protein structure-function relationships, and as a standard in analytical method development.

Basic Information

Product Name	Boc-D-Allylglycine Dcha Salt
CAS No.	221352-64-3
Molecular Formula	C21H38N2O4
Molecular Weight	382.54 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-D-allylglycine dicyclohexylamine salt; (R)-2-((tert-Butoxycarbonyl)amino)pent-4-enoic acid dicyclohexylamine salt; Boc-D-2-amino-4-pentenoic acid DCHA salt; Boc-D-Ag(Dcha); Boc-D-2-Aminopent-4-enoic Acid DCHA Salt; DCHA salt of Boc-D-allylglycine; N-Boc-D-allylglycine DCHA salt
EINECS	Contact for details

Quality Control

Our Boc-D-Allylglycine Dcha Salt is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles for pharmaceutical intermediates, and our quality protocols are designed to meet the stringent requirements of research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed after each use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.