Description

1-Oxaspiro[2.5]Octane, 2-Ethynyl- (9Ci) is a specialized spirocyclic ether building block featuring a reactive ethynyl group. This compound matters as a versatile intermediate for synthesizing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for constructing novel heterocyclic compounds and functionalized polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring spirocyclic or strained ether scaffolds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the unique spiro-oxirane structure can impart specific biological activity.
• Material Science & Polymer Chemistry: Serves as a functional monomer or cross-linking agent for creating specialty polymers with tailored thermal or mechanical properties via click chemistry or other polymerization techniques.
• Organic Synthesis & Methodology Development: A valuable substrate for developing new synthetic routes involving ring-opening reactions, cycloadditions, and modifications of the ethynyl group.
• Ligand & Catalyst Development: Potential precursor for creating novel chelating ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	1-Oxaspiro[2.5]Octane, 2-Ethynyl- (9Ci)
CAS No.	221129-42-6
Molecular Formula	C9H12O
Molecular Weight	136.19 g/mol
Synonyms	2-Ethynyl-1-oxaspiro[2.5]octane; 2-Ethynyloxaspiro[2.5]octane; 1-Oxaspiro[2.5]octane, 2-ethynyl-; Oxirane, 2-ethynylspiro[4.5]decane-2,3-epoxide (related); Ethynyl-substituted spiro-oxirane; Spiro[2.5]octane, 1-oxa-2-ethynyl-
EINECS	Contact for details

Quality Control

Our 1-Oxaspiro[2.5]Octane, 2-Ethynyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥95% (Typical: 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.