Description

(2E)-4-(1-Piperidinyl)-2-Butenoic Acid Hydrochloride is a high-purity, synthetic organic compound primarily used as a key pharmaceutical intermediate. Its defined stereochemistry and piperidine moiety make it a valuable building block for the research and development of novel active pharmaceutical ingredients (APIs). This compound is essential for medicinal chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug molecules, particularly those targeting neurological and cardiovascular pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug discovery programs.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals and advanced materials.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds for biochemical and diagnostic research.

Basic Information

Product Name	(2E)-4-(1-Piperidinyl)-2-Butenoic Acid Hydrochloride
CAS No.	221128-49-0
Molecular Formula	C9H16ClNO2
Molecular Weight	205.68 g/mol
Synonyms	(E)-4-(Piperidin-1-yl)but-2-enoic acid hydrochloride; trans-4-(1-Piperidinyl)-2-butenoic acid hydrochloride; 4-Piperidin-1-ylbut-2-enoic acid hydrochloride; (2E)-4-(Piperidin-1-yl)but-2-enoic acid HCl; 1-Piperidinebut-2-enoic acid hydrochloride (E)-; But-2-enoic acid, 4-(1-piperidinyl)-, hydrochloride, (2E)-; (E)-4-Piperidin-1-yl-2-butenoic acid hydrochloride
EINECS	Contact for details

Quality Control

Our (2E)-4-(1-Piperidinyl)-2-Butenoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.