Description

[4-Bromo-2-(Trifluoromethyl)Phenyl]Hydrazine Hydrochloride is a high-purity, halogenated aromatic hydrazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity of the hydrazine moiety combined with the electron-withdrawing properties of the bromo and trifluoromethyl substituents, enabling precise molecular construction. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of heterocyclic compounds, such as indazoles and pyrazoles, which are core structures in numerous drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of hydrazine-derived compounds.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and halogenated structure.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and labeling strategies in probe and assay development.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for C-N bond formation.
• Dye & Pigment Manufacturing: Utilized as an intermediate in the production of complex azo dyes and high-performance pigments.

Basic Information

Product Name	[4-Bromo-2-(Trifluoromethyl)Phenyl]Hydrazine Hydrochloride
CAS No.	221092-41-7
Molecular Formula	C7H5BrClF3N2
Molecular Weight	289.48 g/mol
Synonyms	4-Bromo-2-(trifluoromethyl)phenylhydrazine hydrochloride; (4-Bromo-2-(trifluoromethyl)phenyl)hydrazine HCl; 1-(4-Bromo-2-(trifluoromethyl)phenyl)hydrazine hydrochloride; 2-Trifluoromethyl-4-bromophenylhydrazine hydrochloride; Hydrazine, [4-bromo-2-(trifluoromethyl)phenyl]-, hydrochloride; 4-Bromo-α,α,α-trifluoro-o-tolylhydrazine hydrochloride
EINECS	Contact for details

Quality Control

Our [4-Bromo-2-(Trifluoromethyl)Phenyl]Hydrazine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity (HPLC), identity (IR, NMR), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.