Description

4-Benzyloxy-2-Fluoro-1-Nitrobenzene is a high-purity fluorinated nitroaromatic compound, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a benzyloxy protecting group and a fluorine atom adjacent to a nitro group, makes it a versatile intermediate for constructing complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic scaffolds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, where the fluorine atom can improve biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Dye and Pigment Manufacturing: Intermediate for producing specialized fluorinated dyes and pigments with unique color fastness and spectral properties.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new reaction pathways in fluoroorganic chemistry.

Basic Information

Product Name	4-Benzyloxy-2-Fluoro-1-Nitrobenzene
CAS No.	221040-07-9
Molecular Formula	C₁₃H₁₀FNO₃
Molecular Weight	247.22 g/mol
Synonyms	2-Fluoro-4-(phenylmethoxy)-1-nitrobenzene; 1-Nitro-4-benzyloxy-2-fluorobenzene; 4-(Benzyloxy)-2-fluoro-1-nitrobenzene; 2-Fluoro-4-benzyloxynitrobenzene; Benzene, 2-fluoro-1-nitro-4-(phenylmethoxy)-; 4-Benzyloxy-2-fluoronitrobenzene
EINECS	Contact for details

Quality Control

Our 4-Benzyloxy-2-Fluoro-1-Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.