Description

7-Chlorofuro[3,2-B]Pyridine-2-Carbonitrile CAS NO 220992-47-2 is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique fused-ring structure, incorporating chlorine and nitrile functional groups, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Serves as a critical building block for creating new generations of herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient fused-ring system.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands for metal-organic frameworks (MOFs) and catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized as a core scaffold for developing fluorescent tags, photoaffinity labels, and other molecular probes for biological target identification and validation.

Basic Information

Item	Information
Product Name	7-Chlorofuro[3,2-B]Pyridine-2-Carbonitrile
CAS No.	220992-47-2
Molecular Formula	C8H3ClN2O
Molecular Weight	178.57 g/mol
Synonyms	7-Chlorofuro[3,2-b]pyridine-2-carbonitrile; 7-Chloro-2-cyanofuro[3,2-b]pyridine; 2-Cyano-7-chlorofuro[3,2-b]pyridine; Furo[3,2-b]pyridine-2-carbonitrile, 7-chloro-; 7-Chloro-2-furo[3,2-b]pyridinecarbonitrile; 220992-47-2; 7-Chloro-furo[3,2-b]pyridine-2-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 7-Chlorofuro[3,2-B]Pyridine-2-Carbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, potency, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.