Description

Cyclohexanecarboxylic Acid, 4-[[(Phenylmethoxy)Carbonyl]Amino]- (9Ci) is a specialized, high-purity organic building block featuring both a carboxylic acid and a protected amino functional group on a cyclohexane ring. This compound matters for its role as a critical chiral intermediate in the synthesis of complex pharmaceutical molecules and advanced agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where its structural motif contributes to biological activity and selectivity.
• Peptidomimetic Research: Serves as a constrained, non-natural amino acid analog in the design of peptide-like molecules with enhanced metabolic stability and bioavailability.
• Ligand and Catalyst Development: Employed as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Acts as a versatile building block for synthesizing specialty chemicals, dyes, and advanced materials requiring specific stereochemistry.
• Academic and Industrial R&D: A valuable compound for methodological studies in organic synthesis, including novel coupling and deprotection strategies.

Basic Information

Item	Detail
Product Name	Cyclohexanecarboxylic Acid, 4-[[(Phenylmethoxy)Carbonyl]Amino]- (9Ci)
CAS No.	220851-34-3
Molecular Formula	C15H19NO4
Molecular Weight	277.32 g/mol
Synonyms	4-[(Benzyloxycarbonyl)amino]cyclohexanecarboxylic acid; 4-(Cbz-Amino)cyclohexanecarboxylic Acid; 4-N-Cbz-aminocyclohexanecarboxylic acid; (1r,4r)-4-[[(Phenylmethoxy)carbonyl]amino]cyclohexanecarboxylic acid; (1s,4s)-4-[[(Phenylmethoxy)carbonyl]amino]cyclohexanecarboxylic acid; 4-(N-Carbobenzyloxyamino)cyclohexanecarboxylic Acid; 4-Amino-1-cyclohexanecarboxylic acid, N-carbobenzoxy-; trans-4-[(Benzyloxycarbonyl)amino]cyclohexanecarboxylic acid
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 4-[[(Phenylmethoxy)Carbonyl]Amino]- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure compliance with exacting research and process development standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if frequent access is required to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (specify isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.