Description

Methyl 8-Bromoquinoline-4-Carboxylate is a high-purity, versatile brominated quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique halogenated structure, which provides a reactive handle for cross-coupling reactions and further functionalization, enabling the synthesis of complex heterocyclic compounds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable building blocks for drug discovery and specialty chemical development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with quinoline-based pharmacophores.
• Agrochemical Research: Used in the development of novel fungicides, herbicides, and insecticides that leverage the biological activity of the quinoline scaffold.
• Material Science: Serves as a building block for creating organic ligands in catalysis and for synthesizing advanced organic electronic materials.
• Chemical Synthesis: An essential reagent for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Academic & R&D: Employed in university and corporate research laboratories for method development and exploring new chemical entities.
• Dye & Pigment Industry: Acts as an intermediate in the synthesis of specialized quinoline-based dyes and colorants.

Basic Information

Product Name	Methyl 8-Bromoquinoline-4-Carboxylate
CAS No.	220844-78-0
Molecular Formula	C11H8BrNO2
Molecular Weight	266.09 g/mol
Synonyms	8-Bromoquinoline-4-carboxylic acid methyl ester; Methyl 8-bromo-4-quinolinecarboxylate; 4-Quinolinecarboxylic acid, 8-bromo-, methyl ester; 8-Bromo-4-quinolinecarboxylic acid methyl ester; Methyl 8-bromoquinoline-4-carboxylate; 220844-78-0; 8-Bromoquinoline-4-methyl carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 8-Bromoquinoline-4-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.