Description

Ethyl 6-Bromoquinoline-4-Carboxylate is a high-purity, versatile brominated quinoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for their synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of quinoline-based drug candidates, including potential kinase inhibitors, antimicrobials, and anticancer agents.
• Agrochemical Research: Used in developing novel pesticides and herbicides, leveraging the quinoline scaffold's bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a substrate for further functionalization to create diverse chemical libraries.
• Academic & R&D: Employed in university and institutional laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	Ethyl 6-Bromoquinoline-4-Carboxylate
CAS No.	220844-77-9
Molecular Formula	C₁₂H₁₀BrNO₂
Molecular Weight	280.12 g/mol
Synonyms	6-Bromoquinoline-4-carboxylic acid ethyl ester; Ethyl 6-bromo-4-quinolinecarboxylate; 4-Quinolinecarboxylic acid, 6-bromo-, ethyl ester; 6-Bromo-4-quinolinecarboxylic acid ethyl ester; Ethyl 6-bromoquinoline-4-carboxylate; 220844-77-9; 6-Bromoquinoline-4-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Bromoquinoline-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.