Description

Ethyl 8-Bromoquinoline-4-Carboxylate is a high-purity, versatile brominated quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an indispensable intermediate for constructing complex molecules with tailored biological and material properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry research for developing new therapeutic agents.
• Agrochemical Research: Used in the development of novel pesticides, herbicides, and fungicides, leveraging the quinoline scaffold's bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced polymers, ligands for metal-organic frameworks (MOFs), and organic electronic materials.
• Chemical Synthesis: Acts as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Heck) and as a substrate for further functionalization to create diverse quinoline libraries.
• Dye and Pigment Industry: Utilized as an intermediate in the synthesis of specialized quinoline-based dyes and colorants.
• Academic & R&D: Essential for fundamental research in organic chemistry, catalysis, and photophysical studies due to its distinct bromine substitution pattern.

Basic Information

Product Name	Ethyl 8-Bromoquinoline-4-Carboxylate
CAS No.	220844-75-7
Molecular Formula	C₁₂H₁₀BrNO₂
Molecular Weight	280.12 g/mol
Synonyms	8-Bromo-4-quinolinecarboxylic acid ethyl ester; Ethyl 8-bromo-4-quinolinecarboxylate; 4-Quinolinecarboxylic acid, 8-bromo-, ethyl ester; 8-Bromoquinoline-4-carboxylic acid ethyl ester; Ethyl 8-bromoquinoline-4-carboxylate; 220844-75-7; Ethyl 8-bromo-4-quinolinecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 8-Bromoquinoline-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.