Description

6-Fluoroquinoline-4-Carboxylic Acid is a high-purity fluorinated quinoline derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its role as a versatile building block for synthesizing novel, potent fluoroquinolone-based active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of next-generation fluoroquinolone antibiotics and other biologically active molecules.
• Agrochemical Research: Used in the development of new crop protection agents and pesticides due to its bioactive quinoline scaffold.
• Chemical Synthesis: Serves as a versatile fluorinated building block for creating complex organic compounds in medicinal chemistry.
• Material Science: Potential applications in the development of organic electronic materials and ligands for catalysis.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting research in heterocyclic chemistry and drug discovery.

Basic Information

Product Name	6-Fluoroquinoline-4-Carboxylic Acid
CAS No.	220844-73-5
Molecular Formula	C10H6FNO2
Molecular Weight	191.16 g/mol
Synonyms	4-Quinolinecarboxylic acid, 6-fluoro-; 6-Fluoro-4-quinolinecarboxylic acid; 6-Fluoroquinoline-4-carboxylic acid; 6-Fluoro-4-carboxyquinoline; 6-Fluoroquinoline-4-carboxylate; 6-Fluoro-4-quinoline carboxylic acid; 6-Fluoro-4-quinolinecarboxylic acid; 6-Fluoroquinoline-4-carboxylic acid (CAS 220844-73-5)
EINECS	Contact for details

Quality Control

Our 6-Fluoroquinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.