Description

Quinoline, 8-[(4S)-4,5-Dihydro-4-(Phenylmethyl)-2-Oxazolyl]- is a specialized chiral oxazoline derivative of quinoline, serving as a high-value synthetic intermediate. This compound is critical for its role in asymmetric synthesis and catalysis, enabling the production of enantiomerically pure compounds. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of chiral drug candidates and complex molecules for medicinal chemistry research.
• Asymmetric Catalysis: Utilized as a ligand precursor or catalyst component in enantioselective organic transformations.
• Chemical Research: Serves as a versatile scaffold in academic and industrial R&D for exploring new reaction pathways and material properties.
• Agrochemical Development: Potential intermediate in the synthesis of advanced, targeted crop protection agents.
• Material Science: Used in the development of specialty polymers and functional organic materials requiring specific chiral centers.

Basic Information

Product Name	Quinoline, 8-[(4S)-4,5-Dihydro-4-(Phenylmethyl)-2-Oxazolyl]-
CAS No.	220628-97-7
Molecular Formula	C19H18N2O
Molecular Weight	290.36 g/mol
Synonyms	8-[(4S)-4-Benzyl-4,5-dihydro-1,3-oxazol-2-yl]quinoline; (S)-8-(4-Benzyl-4,5-dihydrooxazol-2-yl)quinoline; (S)-2-(Quinolin-8-yl)-4-benzyl-4,5-dihydrooxazole; (4S)-4-Benzyl-2-(8-quinolyl)-4,5-dihydro-1,3-oxazole; Chiral Quinoline-Oxazoline Ligand; Quinoline-oxazoline derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data including HPLC purity, chiral purity (enantiomeric excess), and structural confirmation via spectroscopic methods. Certificates of Analysis (COA) are available upon request, detailing batch-specific results for all critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (ee)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.