Description

5,7-Difluoro-4-Hydroxy-2-Phenylquinoline is a high-purity fluorinated quinoline derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmaceutical and agrochemical agents, particularly those targeting specific biological pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates with enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, where the fluorine atoms and quinoline core contribute to biological activity.
• Material Science & OLED Development: Serves as a core structure or ligand in the creation of organic light-emitting diodes (OLEDs) and other electronic materials due to its conjugated system.
• Chemical Biology & Probe Synthesis: Employed as a scaffold for developing fluorescent probes or molecular tags for biological imaging and diagnostic applications.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and heterocyclic synthesis.

Basic Information

Product Name	5,7-Difluoro-4-Hydroxy-2-Phenylquinoline
CAS No.	220598-55-0
Molecular Formula	C₁₅H₉F₂NO
Molecular Weight	257.24 g/mol
Synonyms	4-Hydroxy-5,7-difluoro-2-phenylquinoline; 2-Phenyl-5,7-difluoro-4-quinolinol; 5,7-Difluoro-4-hydroxy-2-phenylquinoline; 4-Quinolinol, 5,7-difluoro-2-phenyl-; 220598-55-0; 5,7-Difluoro-2-phenyl-4-quinolinol
EINECS	Contact for details

Quality Control

Our 5,7-Difluoro-4-Hydroxy-2-Phenylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.