Description

trans-2-(3,5-Dimethoxyphenyl)Cyclopropane-1-Carboxylic Acid is a high-purity, synthetically valuable cyclopropane derivative. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate in modern organic synthesis. It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its cyclopropane scaffold.
• Organic Synthesis Building Block: Employed in asymmetric synthesis and medicinal chemistry for constructing constrained, three-dimensional molecular architectures.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in stereoselective transformations.
• Academic and R&D: Utilized in university and corporate research laboratories for method development and exploring new chemical entities.
• Fine Chemical Production: Incorporated into the manufacture of specialty chemicals requiring high stereochemical purity.

Basic Information

Product Name	trans-2-(3,5-Dimethoxyphenyl)Cyclopropane-1-Carboxylic Acid
CAS No.	220352-05-6
Molecular Formula	C₁₂H₁₄O₄
Molecular Weight	222.24 g/mol
Synonyms	trans-2-(3,5-Dimethoxyphenyl)cyclopropanecarboxylic acid; (1R,2S)-rel-2-(3,5-Dimethoxyphenyl)cyclopropanecarboxylic Acid; 2-(3,5-Dimethoxyphenyl)cyclopropanecarboxylic acid (trans-); Cyclopropanecarboxylic acid, 2-(3,5-dimethoxyphenyl)-, trans-; (1S,2R)-2-(3,5-Dimethoxyphenyl)cyclopropane-1-carboxylic acid; CAS 220352-05-6
EINECS	Contact for details

Quality Control

Our trans-2-(3,5-Dimethoxyphenyl)Cyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and impurity profile analysis by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.