Description

tert-Butyl n-[4-(Aminomethyl)Phenyl]Carbamate CAS NO 220298-96-4 is a high-purity, protected amine derivative serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile and stable amino functionality that can be selectively deprotected under mild acidic conditions, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs), peptide mimetics, and complex specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Peptide Chemistry: Used as a protected amino acid derivative for the solid-phase and solution-phase synthesis of peptides and peptidomimetics.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Acts as a functional monomer or cross-linking agent for creating specialty polymers with amine-reactive sites.
• Bioconjugation: Utilized in linker chemistry for attaching drugs, dyes, or other molecules to antibodies, proteins, or nanoparticles.

Basic Information

Product Name	tert-Butyl n-[4-(Aminomethyl)Phenyl]Carbamate
CAS No.	220298-96-4
Molecular Formula	C12H18N2O2
Molecular Weight	222.28 g/mol
Synonyms	4-[(tert-Butoxycarbonylamino)methyl]aniline; 1-Boc-4-aminobenzylamine; N-Boc-4-aminobenzylamine; tert-Butyl (4-aminobenzyl)carbamate; 4-(Boc-amino)benzylamine; 4-Aminobenzylamine N-Boc derivative; Boc-4-ABn; Boc-PABA
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[4-(Aminomethyl)Phenyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to meeting the stringent requirements of cGMP and ICH guidelines for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.