Description

Ethyl 1-Bromo-4-(2-Bromoethyl)-4A,5,6,7,8,8A-Hexahydronaphthalene-2-Carboxylate is a high-purity, multi-functional brominated intermediate of significant importance in advanced organic synthesis. Its complex, polycyclic structure with dual bromine functionalities makes it a versatile building block for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets, leveraging its complex, bridged-ring scaffold.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the bromine atoms provide reactive sites for further functionalization.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing sophisticated chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty monomers or additives for advanced polymers with specific thermal or optical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms or protein interactions due to its potential as a reactive handle.
• Scalable Process Chemistry: Suitable for optimization into robust, kilogram-scale processes for pilot plant and commercial manufacturing of high-value fine chemicals.

Basic Information

Product Name	Ethyl 1-Bromo-4-(2-Bromoethyl)-4A,5,6,7,8,8A-Hexahydronaphthalene-2-Carboxylate
CAS No.	220151-21-3
Molecular Formula	C₁₅H₂₀Br₂O₂
Molecular Weight	392.13 g/mol
Synonyms	Ethyl 1-bromo-4-(2-bromoethyl)-4a,5,6,7,8,8a-hexahydro-2-naphthoate; 1-Bromo-4-(2-bromoethyl)-4a,5,6,7,8,8a-hexahydronaphthalene-2-carboxylic Acid Ethyl Ester; 2-Naphthalenecarboxylic acid, 1-bromo-4-(2-bromoethyl)-4a,5,6,7,8,8a-hexahydro-, ethyl ester; Ethyl 1,4-Dibromoethylhexahydronaphthalene-2-carboxylate (common name); CAS 220151-21-3; Brominated Hexahydronaphthalene Carboxylate Ester; Dibromoethyl Hexahydronaphthalene Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 1-Bromo-4-(2-Bromoethyl)-4A,5,6,7,8,8A-Hexahydronaphthalene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be sensitive to moisture and prolonged exposure to air; consider storage under an inert atmosphere for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Purity (GC)	≥ 96.0% (Area %)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	< 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.