Description

4(1H)-Quinazolinone, 8-Hydroxy-2-(4-Methylphenyl)- (9Ci) is a specialized quinazolinone derivative, a heterocyclic compound of significant interest in advanced organic synthesis. This compound matters as a versatile and high-purity building block for the development of novel pharmacologically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of potential kinase inhibitors and other therapeutic agents targeting various disease pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting protein kinases.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize biological activity and selectivity.
• Biochemical Tool Compound: Employed in vitro to study enzyme inhibition mechanisms and cellular signaling pathways.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses to construct more elaborate heterocyclic systems.
• Agrochemical Research: Investigated as a potential intermediate for developing new active ingredients with herbicidal or fungicidal properties.
• Academic Research: Used in universities and research institutes for fundamental studies in heterocyclic chemistry and reaction methodology development.

Basic Information

Product Name	4(1H)-Quinazolinone, 8-Hydroxy-2-(4-Methylphenyl)- (9Ci)
CAS No.	220115-32-2
Molecular Formula	C₁₅H₁₂N₂O₂
Molecular Weight	252.27 g/mol
Synonyms	8-Hydroxy-2-(p-tolyl)quinazolin-4(1H)-one; 2-(4-Methylphenyl)-8-hydroxy-4(1H)-quinazolinone; 8-Hydroxy-2-(4-methylphenyl)-1,4-dihydroquinazolin-4-one; 2-(p-Tolyl)-8-hydroxy-4(1H)-quinazolinone; 220115-32-2; 8-Hydroxy-2-(4-methylphenyl)quinazolin-4(3H)-one (tautomer)
EINECS	Contact for details

Quality Control

Our 4(1H)-Quinazolinone, 8-Hydroxy-2-(4-Methylphenyl)- (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profile is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.