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Dichloro{(R)-(+)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}[(1R,2R)-(+)-1,2-Diphenylethylenediamine]Ruthenium(Ii) CAS NO 220114-38-5
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CAS No.:220114-38-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Dichloro{(R)-(+)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}[(1R,2R)-(+)-1,2-Diphenylethylenediamine]Ruthenium(Ii) is a highly specialized, chiral ruthenium complex designed for asymmetric catalysis. This compound matters because it serves as a precise and efficient catalyst for enantioselective hydrogenation and other critical synthetic transformations. It is primarily needed by pharmaceutical intermediates manufacturers and advanced fine chemical producers who require high levels of stereochemical control.
Application
- Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of ketones, imines, and functionalized olefins in pharmaceutical synthesis.
- Pharmaceutical Intermediate Production: Key for manufacturing chiral active pharmaceutical ingredients (APIs) with high enantiomeric excess (ee).
- Fine Chemical Synthesis: Enables the production of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
- Academic and Industrial R&D: Used in method development and discovery chemistry for novel catalytic processes.
- Chiral Ligand Evaluation: Serves as a benchmark or precursor complex for studying the efficacy of novel chiral phosphine ligands.
Basic Information
| Item | Detail |
|---|---|
| Product Name | Dichloro{(R)-(+)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}[(1R,2R)-(+)-1,2-Diphenylethylenediamine]Ruthenium(Ii) |
| CAS No. | 220114-38-5 |
| Molecular Formula | C78H72Cl2N2P2Ru |
| Molecular Weight | 1245.24 g/mol |
| Synonyms | RuCl2[(R)-Xyl-P-Phos][(R,R)-DPEN]; (R,R)-Ru-Xyl-P-Phos-DPEN; Dichloro[(R)-2,2'-bis(di-3,5-xylylphosphino)-1,1'-binaphthyl][(1R,2R)-1,2-diphenylethylenediamine]ruthenium; Ruthenium(II) dichloro complex with (R)-Xyl-P-Phos and (R,R)-DPEN; Noyori-Ikariya type ruthenium catalyst; Asymmetric hydrogenation ruthenium catalyst; Chiral Ru-Diamine-Phosphine complex |
| EINECS | Contact for details |
Quality Control
Our high-purity chiral catalyst is manufactured under controlled conditions to ensure batch-to-batch consistency and optimal catalytic performance. Each lot undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric integrity. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent decomposition. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or ambient light should be avoided.
Specification
| Item | Specification |
|---|---|
| Appearance | Orange to red-brown crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Chiral Purity | ≥ 99.0% ee |
| Residual Solvents (GC) | Meets ICH guidelines |
| Heavy Metals | < 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Why choose US
Trusted Manufacturer
With our own production facilities, we ensure consistent quality, reliable supply, and full traceability.
Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
Advanced R&D Expertise
Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.






