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Dichloro{(R)-(+)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}[(1R,2R)-(+)-1,2-Diphenylethylenediamine]Ruthenium(Ii) CAS NO 220114-38-5


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CAS No.:220114-38-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dichloro{(R)-(+)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}[(1R,2R)-(+)-1,2-Diphenylethylenediamine]Ruthenium(Ii) is a highly specialized, chiral ruthenium complex designed for asymmetric catalysis. This compound matters because it serves as a precise and efficient catalyst for enantioselective hydrogenation and other critical synthetic transformations. It is primarily needed by pharmaceutical intermediates manufacturers and advanced fine chemical producers who require high levels of stereochemical control.

Application

  • Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of ketones, imines, and functionalized olefins in pharmaceutical synthesis.
  • Pharmaceutical Intermediate Production: Key for manufacturing chiral active pharmaceutical ingredients (APIs) with high enantiomeric excess (ee).
  • Fine Chemical Synthesis: Enables the production of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
  • Academic and Industrial R&D: Used in method development and discovery chemistry for novel catalytic processes.
  • Chiral Ligand Evaluation: Serves as a benchmark or precursor complex for studying the efficacy of novel chiral phosphine ligands.

Basic Information

Item Detail
Product Name Dichloro{(R)-(+)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}[(1R,2R)-(+)-1,2-Diphenylethylenediamine]Ruthenium(Ii)
CAS No. 220114-38-5
Molecular Formula C78H72Cl2N2P2Ru
Molecular Weight 1245.24 g/mol
Synonyms RuCl2[(R)-Xyl-P-Phos][(R,R)-DPEN]; (R,R)-Ru-Xyl-P-Phos-DPEN; Dichloro[(R)-2,2'-bis(di-3,5-xylylphosphino)-1,1'-binaphthyl][(1R,2R)-1,2-diphenylethylenediamine]ruthenium; Ruthenium(II) dichloro complex with (R)-Xyl-P-Phos and (R,R)-DPEN; Noyori-Ikariya type ruthenium catalyst; Asymmetric hydrogenation ruthenium catalyst; Chiral Ru-Diamine-Phosphine complex
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Quality Control

Our high-purity chiral catalyst is manufactured under controlled conditions to ensure batch-to-batch consistency and optimal catalytic performance. Each lot undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric integrity. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent decomposition. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or ambient light should be avoided.

Specification

Item Specification
Appearance Orange to red-brown crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Chiral Purity ≥ 99.0% ee
Residual Solvents (GC) Meets ICH guidelines
Heavy Metals < 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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