Description

Dichloro{(R)-(+)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}[(2R)-(-)-1,1-Bis(4-Methoxyphenyl)-3-Methyl-1,2-Butanediamine]Ruthenium(Ii) is a highly sophisticated, chiral ruthenium complex designed for asymmetric catalysis. This compound matters because it serves as a precise and efficient catalyst for enantioselective hydrogenation and other critical synthetic transformations, enabling the production of single-isomer pharmaceutical intermediates and fine chemicals. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require high enantiomeric purity and reliable catalytic performance.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral ketones, olefins, and imines in pharmaceutical intermediate synthesis.
• Pharmaceutical Manufacturing: Key catalyst in the production of chiral active pharmaceutical ingredients (APIs) for drugs targeting central nervous system, cardiovascular, and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Enables the synthesis of chiral flavors, fragrances, and specialty materials with high optical purity.
• Academic & Industrial R&D: A valuable tool for method development and exploring new asymmetric catalytic reactions in process chemistry.
• Ligand-Metal Complex Studies: Serves as a reference compound for studying structure-activity relationships in chiral phosphine-diamine ruthenium catalysts.

Basic Information

Product Name	Dichloro{(R)-(+)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}[(2R)-(-)-1,1-Bis(4-Methoxyphenyl)-3-Methyl-1,2-Butanediamine]Ruthenium(Ii)
CAS No.	220114-32-9
Molecular Formula	C81H78Cl2N2O2P2Ru
Molecular Weight	1320.37 g/mol
Synonyms	RuCl2[(R)-Xyl-P-Phos][(R)-Dpen-C6H4-p-OMe] Complex; (R,R)-Ru-Xyl-P-Phos-Dpen-OMe Catalyst; Dichloro[(R)-2,2'-bis(di-3,5-xylylphosphino)-1,1'-binaphthyl][(2R)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine]ruthenium; Noyori-Ikariya Type Ruthenium Catalyst; Ru-Xyl-P-Phos-Dpen-OMe; Asymmetric Hydrogenation Catalyst 220114-32-9; Chiral Ruthenium Diphosphine Diamine Complex
EINECS	Contact for details

Quality Control

Every batch of our chiral ruthenium catalysts is produced and tested under strict quality management protocols to ensure consistent high performance and enantioselectivity. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as purity (by HPLC/NMR), metal content, chiral purity, and solvent residues. Our quality systems support development under cGMP guidelines for pharmaceutical applications, and we comply with relevant global chemical regulations including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a freezer. This compound is moisture-sensitive (hygroscopic) and easily oxidized; ensure containers are sealed immediately after use to exclude air and moisture. For long-term stability, store in a dedicated, dry freezer.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Ruthenium Content	7.5 - 8.0%
Chloride Content	5.2 - 5.6%
Residual Solvents (GC)	Meet ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.