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Dichloro{(S)-(-)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}[(1S,2S)-(-)-1,2-Diphenylethylenediamine]Ruthenium(Ii) CAS NO 220114-03-4


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CAS No.:220114-03-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dichloro{(S)-(-)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}[(1S,2S)-(-)-1,2-Diphenylethylenediamine]Ruthenium(Ii) is a highly specialized, chiral ruthenium complex designed for asymmetric catalysis. This compound matters because it serves as a precise and efficient catalyst for enantioselective hydrogenation and other critical synthetic transformations. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require high stereoselectivity to produce single-enantiomer active ingredients.

Application

  • Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of ketones, imines, and olefins in pharmaceutical intermediate synthesis.
  • Chiral Ligand Precursor: Serves as a source of the sophisticated (S)-BINAP-derived phosphine ligand for custom catalyst development.
  • Fine Chemical Synthesis: Enables the production of high-value, optically pure compounds for fragrances, flavors, and advanced materials.
  • Academic and Industrial R&D: A critical tool for methodological development in organic synthesis and catalysis research.
  • Process Chemistry Optimization: Used to develop scalable, efficient, and selective manufacturing routes for chiral APIs.

Basic Information

Item Details
Product Name Dichloro{(S)-(-)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}[(1S,2S)-(-)-1,2-Diphenylethylenediamine]Ruthenium(Ii)
CAS No. 220114-03-4
Molecular Formula C78H72Cl2N2P2Ru
Molecular Weight 1248.76 g/mol
Synonyms RuCl2[(S)-(-)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl][(1S,2S)-(-)-1,2-Diphenylethylenediamine]; (S)-RuXYL-DPEN; Dichloro[(S)-(-)-2,2'-bis(di-3,5-xylylphosphino)-1,1'-binaphthyl][(1S,2S)-(-)-1,2-diphenylethylenediamine]ruthenium(II); Chiral Ruthenium BINAP Complex; Asymmetric Hydrogenation Catalyst Ru-XylBINAP/DPEN; Ru-XylBINAP/(S,S)-DPEN Chloride
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Quality Control

Every batch of our chiral ruthenium catalyst is produced and tested under strict quality protocols to ensure exceptional purity and catalytic performance. We provide comprehensive Certificates of Analysis (COA) detailing chiral purity, metal content, and solvent residues. Our quality systems support development under cGMP and ISO 9001 guidelines for traceability and consistency, making this material suitable for demanding research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. This material is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or ambient light should be avoided.

Specification

Item Specification
Appearance Orange to red-brown crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Chiral Purity (HPLC) ≥ 99.0% ee
Ruthenium Content 7.5 - 8.5 %
Solvent Residue (GC) Meet ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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