Description

Methyl 8-Fluoro-4-Hydroxyquinoline-2-Carboxylate is a high-purity fluorinated quinoline derivative, a crucial advanced pharmaceutical intermediate. Its value lies in its role as a key building block for synthesizing novel active pharmaceutical ingredients (APIs) with enhanced biological activity. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those targeting infectious diseases and central nervous system disorders.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging the bioactivity of the quinoline and fluorine moieties.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for medicinal chemistry, enabling the creation of compound libraries for high-throughput screening.
• Fluorescent Probe Development: Potential use in the research and development of diagnostic agents and bio-imaging materials due to its quinoline-based fluorophore structure.
• Material Science Research: Investigated for the synthesis of organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	Methyl 8-Fluoro-4-Hydroxyquinoline-2-Carboxylate
CAS No.	219949-89-0
Molecular Formula	C11H8FNO3
Molecular Weight	221.19 g/mol
Synonyms	8-Fluoro-4-hydroxyquinoline-2-carboxylic acid methyl ester; Methyl 8-fluoro-4-hydroxy-2-quinolinecarboxylate; 2-Quinolinecarboxylic acid, 8-fluoro-4-hydroxy-, methyl ester; 8-Fluoro-4-hydroxy-2-quinolinecarboxylic acid methyl ester; 219949-89-0; Methyl 8-fluoro-4-oxo-1,4-dihydroquinoline-2-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 8-Fluoro-4-Hydroxyquinoline-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.