Description

(R)-(-)-1-(α-Aminobenzyl)-2-Naphthol CAS NO 219897-35-5 is a high-purity chiral intermediate of significant importance in asymmetric synthesis. Its primary value lies in its utility as a key building block for the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research and manufacturing organizations in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop optically active compounds with high stereoselectivity.

Application

• Chiral Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands used in asymmetric catalysis.
• Pharmaceutical Intermediate: A critical building block in the synthesis of enantiopure active pharmaceutical ingredients (APIs), particularly for central nervous system and cardiovascular drugs.
• Asymmetric Synthesis: Employed in stereoselective carbon-carbon bond-forming reactions, such as asymmetric Henry reactions or additions.
• Agrochemical Research: Used in the development of chiral pesticides and herbicides where specific stereochemistry is required for bioactivity.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and catalysis research at universities and corporate labs.

Basic Information

Item	Details
Product Name	(R)-(-)-1-(α-Aminobenzyl)-2-Naphthol
CAS No.	219897-35-5
Molecular Formula	C17H15NO
Molecular Weight	249.31 g/mol
Synonyms	(R)-1-(α-Aminobenzyl)-2-naphthol; (R)-1-(Aminophenylmethyl)-2-naphthalenol; (R)-1-(1-Amino-1-phenylethyl)-2-naphthol (common misassignment, verify structure); (R)-ABNO; (R)-(-)-1-(1-Aminoethyl)-2-naphthol (related compound); (R)-Naphthyl Amino Alcohol Derivative; (R)-1-(α-Amino-benzyl)-2-naphthol; (R)-2-Naphthol, 1-(α-aminobenzyl)-
EINECS	Contact for details

Quality Control

Our (R)-(-)-1-(α-Aminobenzyl)-2-Naphthol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.