Description

1H-Pyrrolo[3,2-C]Pyridine-1-Carboxylic Acid,2,3-Dihydro-1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of critical importance for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) therapeutic areas. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel drug candidates targeting specific biological pathways.
• Oncology Research: Used in the development of kinase inhibitors and other targeted cancer therapies due to its privileged scaffold.
• CNS Drug Discovery: Employed as a building block for compounds intended to cross the blood-brain barrier for treating neurological disorders.
• Chemical Biology: Utilized in the creation of molecular probes and tool compounds for studying enzyme function and cellular signaling.
• Process Chemistry & Scale-Up: Provides a defined, high-quality starting material for optimizing synthetic routes from laboratory to pilot and commercial scale.
• Custom Synthesis: Acts as a specialized substrate for contract research and manufacturing services requiring specific molecular architectures.

Basic Information

Product Name	1H-Pyrrolo[3,2-C]Pyridine-1-Carboxylic Acid,2,3-Dihydro-1,1-Dimethylethyl Ester
CAS No.	219834-81-8
Molecular Formula	C13H16N2O2
Molecular Weight	232.28 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-2,3-dihydro-1H-pyrrolo[3,2-c]pyridine; 2,3-Dihydro-1H-pyrrolo[3,2-c]pyridine-1-carboxylic acid 1,1-dimethylethyl ester; tert-Butyl 2,3-dihydro-1H-pyrrolo[3,2-c]pyridine-1-carboxylate; 1-Boc-2,3-dihydro-1H-pyrrolo[3,2-c]pyridine; Boc-DHP; 1-N-Boc-2,3-dihydropyrrolo[3,2-c]pyridine; 1H-Pyrrolo[3,2-c]pyridine-1-carboxylic acid, 2,3-dihydro-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[3,2-C]Pyridine-1-Carboxylic Acid,2,3-Dihydro-1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.