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Methyl (Phenyl 5-Acetamido-4,7,8-Tri-o-Acetyl-9-Azido-3,5,9-Trideoxy-2-Thio-D-Glycero-β-D-Galacto-2-Nonulopyranosid)Onate CAS NO 219814-65-0


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CAS No.:219814-65-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methyl (Phenyl 5-Acetamido-4,7,8-Tri-o-Acetyl-9-Azido-3,5,9-Trideoxy-2-Thio-D-Glycero-β-D-Galacto-2-Nonulopyranosid)Onate is a sophisticated, high-purity synthetic intermediate primarily used in advanced carbohydrate and sialic acid chemistry. This compound is critical for researchers and manufacturers developing novel glycoconjugates, sialoside mimetics, and bioactive molecules. It is an essential building block for pharmaceutical R&D, particularly in the synthesis of potential antiviral agents, neuraminidase inhibitors, and diagnostic tools targeting glycan-mediated biological processes.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of complex sialic acid derivatives and neuraminidase inhibitors for antiviral drug discovery.
  • Glycobiology Research: Essential building block for constructing structurally defined sialosides and glycoconjugates to study carbohydrate-protein interactions.
  • Diagnostic Reagent Synthesis: Used in the development of enzyme substrates, probes, and labeled compounds for diagnostic assays targeting sialidases and lectins.
  • Medicinal Chemistry: Serves as a versatile scaffold for creating glycomimetics and drug candidates that modulate cell surface recognition processes.
  • Bioconjugation: The reactive azido and thio groups enable site-specific conjugation strategies, such as click chemistry, for labeling and linker attachment.
  • Academic & Industrial R&D: A valuable tool for synthetic chemists and biochemists exploring the structure-activity relationships of sialic acid-containing molecules.

Basic Information

Product Name Methyl (Phenyl 5-Acetamido-4,7,8-Tri-o-Acetyl-9-Azido-3,5,9-Trideoxy-2-Thio-D-Glycero-β-D-Galacto-2-Nonulopyranosid)Onate
CAS No. 219814-65-0
Molecular Formula C26H32N4O11S
Molecular Weight 608.62 g/mol
Synonyms Phenyl 5-acetamido-4,7,8-tri-O-acetyl-9-azido-3,5,9-trideoxy-2-thio-D-glycero-β-D-galacto-2-nonulopyranosidonic acid methyl ester; Methyl 5-acetamido-9-azido-4,7,8-tri-O-acetyl-3,5,9-trideoxy-2-thio-D-glycero-β-D-galacto-non-2-ulopyranosidonate; Sialic Acid Derivative; Thiosialoside Methyl Ester; Azido Sialic Acid Intermediate; 9-Azido Neu5Ac Derivative
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Quality Control

Every batch of our Methyl (Phenyl 5-Acetamido-4,7,8-Tri-o-Acetyl-9-Azido-3,5,9-Trideoxy-2-Thio-D-Glycero-β-D-Galacto-2-Nonulopyranosid)Onate undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of pharmaceutical R&D and advanced chemical synthesis. Certificates of Analysis (COA) detailing purity, chromatographic data, and spectroscopic identification are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled temperature, typically between 2°C and 8°C for long-term stability, or as specified on the label. Due to its hygroscopic (moisture-sensitive) nature, the container should be sealed under an inert atmosphere or with desiccant after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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