Description

Ecabet Sodium Hydrate is a sodium salt derivative of the diterpenoid compound ecabet, known for its potent gastroprotective and anti-ulcer properties. This compound is a critical active pharmaceutical ingredient (API) and a valuable intermediate in advanced pharmaceutical synthesis. It is primarily utilized by pharmaceutical manufacturers and research institutions focused on developing and producing treatments for gastrointestinal disorders, including gastritis and peptic ulcers.

Application

• Pharmaceutical API: Serves as the primary active ingredient in prescription medications for the treatment and prevention of gastric and duodenal ulcers.
• Gastroprotective Formulations: Used in the development of gastroprotective drugs that enhance mucosal defense mechanisms in the stomach.
• Clinical Research: Employed as a reference standard and key material in preclinical and clinical studies investigating new gastrointestinal therapies.
• Intermediate for Analog Synthesis: Acts as a crucial synthetic building block for creating novel ecabet derivatives with potentially enhanced pharmacological profiles.
• Veterinary Medicine: Incorporated into formulations for treating gastrointestinal conditions in animals.

Basic Information

Item	Details
Product Name	Ecabet Sodium Hydrate
CAS No.	219773-47-4
Molecular Formula	C20H27NaO5S
Molecular Weight	402.48 g/mol
Synonyms	Ecabet Sodium; Sodium Ecabet; Ecaben Sodium; (+)-(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-6-sulfo-1-phenanthrenecarboxylic Acid Sodium Salt; 12-Sulfodehydroabietic Acid Sodium Salt; TA-2711
EINECS	Contact for details

Quality Control

Our Ecabet Sodium Hydrate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and stringent limits for residual solvents and related substances. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with current Good Manufacturing Practice (cGMP) and ICH Q7 guidelines for active pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Complies with Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.