Description

Methyl 4-Bromoquinoline-6-Carboxylate CAS NO 219763-85-6 is a high-purity brominated quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in drug discovery, agrochemical synthesis, and the development of advanced materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-infective research programs.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and pesticides, leveraging the quinoline core's bioactivity.
• Material Science Research: Serves as a precursor for creating organic semiconductors, ligands for catalysis, and specialty polymers.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploratory synthesis.
• Fine Chemical Manufacturing: An intermediate in the multi-step production of complex, high-value specialty chemicals.

Basic Information

Product Name	Methyl 4-Bromoquinoline-6-Carboxylate
CAS No.	219763-85-6
Molecular Formula	C11H8BrNO2
Molecular Weight	266.09 g/mol
Synonyms	4-Bromo-6-quinolinecarboxylic acid methyl ester; Methyl 4-bromo-6-quinolinecarboxylate; 4-Bromoquinoline-6-carboxylic acid methyl ester; 6-(Methoxycarbonyl)-4-bromoquinoline; 4-Bromo-6-(methoxycarbonyl)quinoline; Quinoline, 4-bromo-6-carbomethoxy-; Methyl ester of 4-bromoquinoline-6-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Bromoquinoline-6-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your synthetic workflows. All material is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment, supporting compliance with research and cGMP standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.