Description

S-3,3'-Diiodo-2,2'-Bis(Methoxymethoxy)1,1'-Binaphthalene is a specialized chiral binaphthyl derivative, a key synthetic intermediate in advanced organic chemistry. This compound matters for its role as a crucial building block in the synthesis of chiral ligands and catalysts, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel asymmetric synthesis routes.

Application

• Chiral Ligand Synthesis: A critical precursor for constructing sophisticated phosphine and N-heterocyclic carbene (NHC) ligands used in asymmetric catalysis.
• Pharmaceutical Intermediate: Employed in the research and development of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Catalyst Development: Serves as a core scaffold for developing novel organocatalysts and transition metal catalysts for stereoselective transformations like hydrogenation and cross-coupling.
• Material Science Research: Used in the synthesis of chiral polymers and liquid crystals for advanced optical and electronic materials.
• Agrochemical Synthesis: A building block for creating chiral herbicides, fungicides, and plant growth regulators with enhanced efficacy and environmental profile.
• Academic & Process Chemistry: A valuable reagent for methodological studies in organic synthesis and for scaling up enantioselective processes.

Basic Information

Product Name	S-3,3'-Diiodo-2,2'-Bis(Methoxymethoxy)1,1'-Binaphthalene
CAS No.	219583-87-6
Molecular Formula	C₂₄H₂₂I₂O₄
Molecular Weight	668.24 g/mol
Synonyms	(S)-3,3'-Diiodo-2,2'-bis(methoxymethoxy)-1,1'-binaphthalene; (S)-3,3'-Diiodo-2,2'-bis(MOM)-1,1'-binaphthyl; S-BINOL-I2(MOM)2; (S)-3,3'-Diiodo-BINOL MOM Ether; (S)-3,3'-Diiodo-2,2'-di(methoxymethoxy)-1,1'-binaphthyl; (S)-3,3'-Diiodo-2,2'-bis(methoxymethyloxy)-1,1'-binaphthalene; (S)-3,3'-Diiodo-2,2'-bis(methoxymethoxy)binaphthyl
EINECS	Contact for details

Quality Control

Our S-3,3'-Diiodo-2,2'-Bis(Methoxymethoxy)1,1'-Binaphthalene is manufactured under strict quality control protocols to ensure high chemical purity and enantiomeric excess (ee) suitable for demanding synthetic applications. Each batch is characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing purity, chiral purity, and identity are provided to guarantee consistency and support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged manipulations to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.