Description

3-Chloro-1H-Indole-6-Carboxylic Acid is a high-purity, functionalized indole derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated indole scaffold makes it a versatile intermediate for constructing complex molecules with potential biological activity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for use in medicinal chemistry, drug discovery, and the development of novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for method development, structure-activity relationship (SAR) studies, and combinatorial chemistry.
• Bioconjugation & Probe Synthesis: The carboxylic acid group allows for facile conjugation, making it useful for creating fluorescent probes or biochemical tools.

Basic Information

Product Name	3-Chloro-1H-Indole-6-Carboxylic Acid
CAS No.	219508-17-5
Molecular Formula	C9H6ClNO2
Molecular Weight	195.60 g/mol
Synonyms	3-Chloro-6-carboxyindole; 6-Carboxy-3-chloroindole; 3-Chloroindole-6-carboxylic acid; 1H-Indole-6-carboxylic acid, 3-chloro-; 219508-17-5; 3-Chloro-1H-indole-6-carboxylic acid; 3-Cl-6-COOH-Indole
EINECS	Contact for details

Quality Control

Our 3-Chloro-1H-Indole-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.