Description

(1S,2S)-(-)-[1,2-Cyclohexanediamino-N,N'-Bis(3,5-Di-T-Butylsalicylidene)]Chromium(III) Chloride is a highly specialized chiral salen-type organometallic complex, valued for its role as a stereoselective catalyst in asymmetric synthesis. Its precise stereochemistry and chromium(III) center make it a critical component for inducing high enantioselectivity in key organic transformations. This compound is essential for R&D and production chemists in the pharmaceutical, fine chemical, and advanced materials sectors seeking efficient routes to chiral molecules.

Application

• Asymmetric Catalysis: A key catalyst for enantioselective epoxidation, cyclopropanation, and other C-C/C-H bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Used in the production of chiral active pharmaceutical ingredients (APIs) requiring high optical purity.
• Fine Chemical Manufacturing: Enables the synthesis of complex, high-value specialty chemicals with defined stereochemistry.
• Polymer Science Research: Investigated as a catalyst for the stereoregular polymerization of olefins and other monomers.
• Academic & Industrial R&D: A valuable tool for developing new catalytic methodologies and exploring novel reaction pathways.
• Ligand Precursor: Can serve as a starting material for generating modified chiral ligand libraries.

Basic Information

Product Name	(1S,2S)-(-)-[1,2-Cyclohexanediamino-N,N'-Bis(3,5-Di-T-Butylsalicylidene)]Chromium(III) Chloride
CAS No.	219143-92-7
Molecular Formula	C38H56ClCrN2O2
Molecular Weight	660.29 g/mol
Synonyms	(1S,2S)-(-)-1,2-Cyclohexanediamino-N,N'-bis(3,5-di-tert-butylsalicylidene)chromium(III) chloride; (S,S)-(-)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminochromium(III) chloride; (S,S)-Jacobsen's Chromium(III) Catalyst; (S,S)-Cr(III)(salen)Cl; Chiral Chromium Salen Complex; (S,S)-(-)-Chromium Salen Catalyst; Asymmetric Chromium Catalyst; (1S,2S)-Cyclohexanediamine Salen CrCl
EINECS	Contact for details

Quality Control

Our (1S,2S)-(-)-[1,2-Cyclohexanediamino-N,N'-Bis(3,5-Di-T-Butylsalicylidene)]Chromium(III) Chloride is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and key spectroscopic data. We adhere to cGMP standards where applicable to meet the stringent requirements of pharmaceutical and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere. This compound is moisture-sensitive and should be handled in a dry environment to maintain stability and catalytic activity.

Specification

Item	Specification
Appearance	Dark green to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Chromium Content	7.0 - 8.5 %
Solubility	Soluble in dichloromethane, toluene; sparingly soluble in hexanes

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.