Description

(S)-3-Ethylmorpholine Hydrochloride is a high-purity chiral building block and intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key precursor for the development of active pharmaceutical ingredients (APIs), particularly in the creation of enantiomerically pure compounds. This product is essential for research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require a reliable source of a specific stereoisomer for process development and scale-up.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral research.
• Asymmetric Synthesis: Used as a ligand or catalyst component in enantioselective reactions to produce optically active molecules.
• Agrochemical Development: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where stereochemical purity is paramount.
• Academic & Industrial R&D: A valuable reagent for medicinal chemistry and process chemistry research in both university and corporate laboratories.
• Custom Synthesis: Acts as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	(S)-3-Ethylmorpholine Hydrochloride
CAS No.	218594-88-8
Molecular Formula	C6H13NO·HCl
Molecular Weight	151.64 g/mol
Synonyms	(S)-3-Ethylmorpholine HCl; (S)-3-Ethylmorpholine Hydrochloride Salt; (S)-3-Ethyl-1,4-oxazinane hydrochloride; (S)-3-Ethyltetrahydro-1,4-oxazine hydrochloride; (S)-3-Ethylmorpholine monohydrochloride; (S)-3-Ethyl-4-morpholinamine hydrochloride; Morpholine, 3-ethyl-, hydrochloride, (S)-; (3S)-3-Ethylmorpholine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-3-Ethylmorpholine Hydrochloride is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC, NMR, and residual solvent analysis, to meet the stringent requirements of pharmaceutical development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.