Description

1H-Indene-1,2-Diamine,2,3-Dihydro-,(1R,2R)-(9Ci) is a high-purity, chiral diamine building block of significant interest in advanced organic synthesis. Its rigid, fused-ring structure and defined stereochemistry make it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Catalyst Ligand: Serves as a precursor for synthesizing sophisticated chiral ligands used in asymmetric hydrogenation and other enantioselective catalytic processes.
• Agrochemical Synthesis: Employed in the development of new, stereospecific herbicides, fungicides, and insecticides where specific chirality is crucial for bioactivity.
• Advanced Material Research: Used in the synthesis of specialty polymers and organic frameworks where its diamine functionality and rigid backbone can impart specific mechanical or chemical properties.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and for exploring new reaction pathways in process chemistry.

Basic Information

Product Name	1H-Indene-1,2-Diamine,2,3-Dihydro-,(1R,2R)-(9Ci)
CAS No.	218151-48-5
Molecular Formula	C9H12N2
Molecular Weight	148.21 g/mol
Synonyms	(1R,2R)-1,2-Diaminoindane; (1R,2R)-1,2-Diamino-2,3-dihydro-1H-indene; (1R,2R)-Indane-1,2-diamine; (1R,2R)-1,2-Diaminoindan; (1R,2R)-1,2-Dihydro-1H-indene-1,2-diamine; (1R,2R)-1,2-Diamino-1H-indene,2,3-dihydro-; (1R,2R)-1,2-Diamino-2,3-dihydroindene; (1R,2R)-1,2-Diamino-1H-indene
EINECS	Contact for details

Quality Control

Our 1H-Indene-1,2-Diamine,2,3-Dihydro-,(1R,2R)-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, enantiomeric excess, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.