Description

2-(Chloromethyl)-2-Methyl-3-(4-Methylphenyl)-1,2,3,4-Tetrahydroquinazolin-4-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Serves as a building block for developing new herbicides and pesticides with specific modes of action.
• Organic Synthesis: Used in academic and industrial R&D for constructing complex nitrogen-containing heterocycles.
• Chemical Biology: Employed as a molecular probe or scaffold in medicinal chemistry programs for hit-to-lead optimization.
• Material Science: Potential intermediate for the synthesis of specialty polymers or functional materials.

Basic Information

Product Name	2-(Chloromethyl)-2-Methyl-3-(4-Methylphenyl)-1,2,3,4-Tetrahydroquinazolin-4-One
CAS No.	217461-89-7
Molecular Formula	C18H17ClN2O
Molecular Weight	312.79 g/mol
Synonyms	2-(Chloromethyl)-2-methyl-3-(p-tolyl)-1,2,3,4-tetrahydroquinazolin-4-one; 3-(4-Methylphenyl)-2-(chloromethyl)-2-methyl-1,2,3,4-tetrahydro-4-quinazolinone; 4(1H)-Quinazolinone, 1,2,3,4-tetrahydro-2-(chloromethyl)-2-methyl-3-(4-methylphenyl)-; CAS 217461-89-7
EINECS	Contact for details

Quality Control

Our production of 2-(Chloromethyl)-2-Methyl-3-(4-Methylphenyl)-1,2,3,4-Tetrahydroquinazolin-4-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.