Description

2-(Chloromethyl)-2-Methyl-3-Phenyl-1,2,3,4-Tetrahydroquinazolin-4-One is a high-value, synthetically versatile quinazolinone derivative. This compound serves as a critical pharmaceutical intermediate and organic building block for advanced chemical synthesis. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Building block for developing advanced pesticides, herbicides, and fungicides with enhanced efficacy and selectivity.
• Organic Light-Emitting Diodes (OLEDs): Used in the research and development of electron-transporting or host materials for optoelectronic devices.
• Ligand and Catalyst Development: Serves as a scaffold for creating novel ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic and R&D Laboratories: Employed in medicinal chemistry programs and methodological studies for constructing complex heterocyclic systems.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, dyes, and advanced polymers.

Basic Information

Product Name	2-(Chloromethyl)-2-Methyl-3-Phenyl-1,2,3,4-Tetrahydroquinazolin-4-One
CAS No.	217461-83-1
Molecular Formula	C₁₇H₁₅ClN₂O
Molecular Weight	298.76 g/mol
Synonyms	2-(Chloromethyl)-2-methyl-3-phenyl-1,2,3,4-tetrahydro-4-quinazolinone; 2-Methyl-2-chloromethyl-3-phenyl-1,2,3,4-tetrahydroquinazolin-4-one; 3-Phenyl-2-(chloromethyl)-2-methyl-1,2,3,4-tetrahydroquinazolin-4-one; 4(1H)-Quinazolinone, 2-(chloromethyl)-1,2,3,4-tetrahydro-2-methyl-3-phenyl-; Tetrahydroquinazolinone derivative
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-2-Methyl-3-Phenyl-1,2,3,4-Tetrahydroquinazolin-4-One is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We can supply material compliant with ICH guidelines for pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.