Description

Ethyl 3-(6-Chloro-3-Pyridyl)-3-Oxopropanoate is a high-purity, versatile chemical intermediate with significant utility in advanced organic synthesis. Its core value lies in its reactive β-ketoester functionality attached to a chlorinated pyridine ring, making it a critical building block for constructing complex molecular architectures. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for neurological and anti-infective agents.
• Agrochemical Synthesis: Serves as a crucial building block for developing next-generation insecticides and herbicides, leveraging the bioactive chloronicotinyl moiety.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new heterocyclic compounds and conducting structure-activity relationship (SAR) studies.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fine chemicals and specialty materials requiring precise molecular control.

Basic Information

Product Name	Ethyl 3-(6-Chloro-3-Pyridyl)-3-Oxopropanoate
CAS No.	216317-64-5
Molecular Formula	C10H10ClNO3
Molecular Weight	227.64 g/mol
Synonyms	Ethyl 3-(6-chloropyridin-3-yl)-3-oxopropanoate; 3-Oxobutanoic acid, 3-(6-chloro-3-pyridinyl)-, ethyl ester; Ethyl 6-chloronicotinoylacetate; 6-Chloronicotinoylacetic acid ethyl ester; Ethyl (6-chloro-3-pyridinyl)oxoacetate; 216317-64-5; AKOS BRN-0715
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-(6-Chloro-3-Pyridyl)-3-Oxopropanoate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.