Description

1-[(2S)-2-Pyrrolidinylmethyl]-Piperidine Dihydrochloride is a high-purity chiral piperidine derivative, supplied as a dihydrochloride salt for enhanced stability and handling. This compound serves as a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel drug candidates.
• Chemical Research & Development: Used as a building block for constructing complex nitrogen-containing heterocycles and alkaloid analogs.
• Ligand Synthesis: Employed in the preparation of chiral ligands for asymmetric catalysis.
• Medicinal Chemistry: Integral for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development.

Basic Information

Product Name	1-[(2S)-2-Pyrrolidinylmethyl]-Piperidine Dihydrochloride
CAS No.	215918-57-3
Molecular Formula	C10H22Cl2N2
Molecular Weight	241.20 g/mol
Synonyms	(S)-1-((Pyrrolidin-2-yl)methyl)piperidine dihydrochloride; (2S)-1-(Piperidin-1-ylmethyl)pyrrolidine dihydrochloride; (S)-1-(Piperidin-1-ylmethyl)pyrrolidine dihydrochloride; 1-[(2S)-2-Pyrrolidinylmethyl]piperidine dihydrochloride; 1-[(S)-2-Pyrrolidinylmethyl]piperidine dihydrochloride; (S)-PMP Dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-[(2S)-2-Pyrrolidinylmethyl]-Piperidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.