Description

4-[2-(2-Oxo-Pyrrolidin-1-Yl)-Ethoxy]-Benzoic Acid is a high-purity organic compound serving as a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis. Its molecular structure, featuring both a benzoic acid moiety and a pyrrolidinone group linked by an ethoxy spacer, makes it a valuable precursor for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new therapeutic agents or high-value functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• API Development: Serves as a precursor for the manufacture of Active Pharmaceutical Ingredients (APIs) requiring specific lactam and aromatic carboxylic acid functionalities.
• Fine Chemical Synthesis: Used in the production of specialty chemicals, dyes, and advanced polymers where its bifunctional nature is advantageous.
• Agrochemical Research: Employed as an intermediate in developing new herbicides, fungicides, or plant growth regulators.
• Bioconjugation & Linker Chemistry: The carboxylic acid group allows for coupling reactions, making it useful in creating molecular probes or drug-linker systems for targeted therapies.
• Academic & Industrial R&D: A valuable reagent for medicinal chemistry programs and process development in contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name	4-[2-(2-Oxo-Pyrrolidin-1-Yl)-Ethoxy]-Benzoic Acid
CAS No.	215656-70-5
Molecular Formula	C14H17NO4
Molecular Weight	263.29 g/mol
Synonyms	1-[2-(4-Carboxyphenoxy)ethyl]-2-pyrrolidinone; 4-[2-(2-Oxo-1-pyrrolidinyl)ethoxy]benzoic Acid; Benzoic acid, 4-[2-(2-oxo-1-pyrrolidinyl)ethoxy]-; UNII-6V9E3S3W6R; 4-(2-(2-Oxopyrrolidin-1-yl)ethoxy)benzoic acid; 1-[2-(4-Carboxyphenoxy)ethyl]pyrrolidin-2-one; 4-(2-(2-Oxopyrrolidin-1-yl)ethoxy)benzoic acid; 4-(2-(2-Oxopyrrolidin-1-yl)ethoxy)benzoic acid (CAS 215656-70-5)
EINECS	Contact for details

Quality Control

Our 4-[2-(2-Oxo-Pyrrolidin-1-Yl)-Ethoxy]-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥98% by HPLC), residual solvents, and specific impurities is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.