Description

(3R,2S)-2,3-Diaminobutyric Acid 2Hcl CAS NO 215652-51-0 is a high-purity, non-proteinogenic amino acid derivative featuring two chiral centers, making it a valuable chiral building block and intermediate. This compound is essential for the synthesis of complex molecules where precise stereochemistry is critical for biological activity and function. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, peptide mimetics, and advanced chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for antibiotics, enzyme inhibitors, and receptor antagonists.
• Peptide Synthesis: Used to incorporate the unique 2,3-diaminobutyric acid (Dab) residue into custom peptides and peptidomimetics for structure-activity relationship (SAR) studies and drug discovery.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies, metabolic pathway analysis, and as a precursor for labeled compounds in tracer experiments.
• Ligand and Catalyst Development: Employed in the synthesis of chiral ligands for asymmetric catalysis and metal complexes due to its chelating diamino acid structure.
• Agrochemical Research: Potential intermediate in the synthesis of specialized, biologically active compounds for crop protection science.

Basic Information

Item	Details
Product Name	(3R,2S)-2,3-Diaminobutyric Acid 2Hcl
CAS No.	215652-51-0
Molecular Formula	C₄H₁₀N₂O₂ • 2HCl
Molecular Weight	215.06 g/mol
Synonyms	(2S,3R)-2,3-Diaminobutanoic Acid Dihydrochloride; (3R,2S)-2,3-Diaminobutyric Acid Dihydrochloride; D-erythro-2,3-Diaminobutyric Acid Hydrochloride; (2S,3R)-DAB•2HCl; L-threo-2,3-Diaminobutyric Acid Dihydrochloride (enantiomer); 2,3-Diamino-DL-butyric Acid Dihydrochloride (racemic mix); Amino Acid Derivative AID 215652; 2,3-DAB•2HCl
EINECS	Contact for details

Quality Control

Every batch of (3R,2S)-2,3-Diaminobutyric Acid 2Hcl is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, meeting the exacting standards required for research and development. A Certificate of Analysis (COA) detailing specifications such as chiral purity (HPLC), assay, and residual solvents is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.