Description

(2S)-2-((1R,3Ar,7Ar)-4-((tert-Butyldimethylsilyl)Oxy)-7A-Methyloctahydro-1H-Inden-1-Yl)Propan-1-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its complex, stereochemically defined structure. This compound is a critical building block in the synthesis of complex organic molecules, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of steroid-based therapeutics and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex steroid derivatives and other bioactive molecules.
• Steroid Analog Research: Used in medicinal chemistry for the research and development of novel steroid receptor modulators.
• Process Chemistry: Serves as a critical intermediate in the scale-up and optimization of API manufacturing processes.
• Asymmetric Synthesis: Employed in advanced organic synthesis to introduce specific stereocenters into target molecular frameworks.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(2S)-2-((1R,3Ar,7Ar)-4-((tert-Butyldimethylsilyl)Oxy)-7A-Methyloctahydro-1H-Inden-1-Yl)Propan-1-Ol
CAS No.	215509-33-4
Molecular Formula	C20H40O2Si
Molecular Weight	340.62 g/mol
Synonyms	(2S)-2-[(1R,3aR,7aR)-4-[(tert-Butyldimethylsilyl)oxy]-7a-methyloctahydro-1H-inden-1-yl]propan-1-ol; (1R,3aR,7aR)-1-[(2S)-2-Hydroxypropyl]-7a-methyloctahydro-1H-inden-4-yl tert-Butyldimethylsilyl Ether; TBDMS-protected steroid alcohol intermediate; Steroid-TBDMS ether propanol derivative
EINECS	Contact for details

Quality Control

Our (2S)-2-((1R,3Ar,7Ar)-4-((tert-Butyldimethylsilyl)Oxy)-7A-Methyloctahydro-1H-Inden-1-Yl)Propan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high stereochemical purity and chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.