Description

Fmoc-Piperazine Hydrochloride CAS NO 215190-22-0 is a high-purity, protected piperazine derivative widely used as a critical building block in solid-phase peptide synthesis (SPPS). Its primary value lies in its role as an Fmoc-protected diamine linker, enabling the controlled introduction of the piperazine moiety into peptide chains and other complex organic molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, high-quality intermediates for developing new therapeutic peptides, peptidomimetics, and specialized chemical entities.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected intermediate for incorporating the piperazine scaffold into peptide backbones.
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly in oncology, neurology, and antimicrobial therapies.
• Peptidomimetic Design: Serves as a versatile building block for creating non-peptide compounds that mimic peptide activity with enhanced stability.
• Chemical Biology & Proteomics: Employed in the synthesis of probes, tags, and linkers for studying protein-protein interactions and cellular processes.
• Combinatorial Chemistry: A valuable reagent for generating diverse chemical libraries for high-throughput screening in drug discovery.
• Material Science: Potential use in the synthesis of functional polymers and dendrimers with specific chemical properties.

Basic Information

Product Name	Fmoc-Piperazine Hydrochloride
CAS No.	215190-22-0
Molecular Formula	C19H21ClN2O2
Molecular Weight	344.84 g/mol
Synonyms	1-Fmoc-piperazine hydrochloride; N-Fmoc-piperazine hydrochloride; 1-[(9H-Fluoren-9-ylmethoxy)carbonyl]piperazine hydrochloride; Fmoc-Pip-OH·HCl; 9-Fluorenylmethyl N-piperazinylcarbamate hydrochloride; Piperazine, 1-[(9H-fluoren-9-ylmethoxy)carbonyl]-, hydrochloride (1:1); N-α-Fmoc-piperazine hydrochloride
EINECS	Contact for details

Quality Control

Our Fmoc-Piperazine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.