Description

T-Butyl 4-Carboxybenzamide CAS NO 215118-68-6 is a high-purity organic intermediate featuring a tert-butyl-protected carboxylic acid group and a benzamide moiety. This compound is valued for its role as a versatile building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material industries for constructing active pharmaceutical ingredients (APIs) and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Employed to introduce amide and protected carboxyl functionalities into polymer chains, enhancing material properties.
• Peptidomimetics Research: The benzamide structure makes it useful in designing and synthesizing peptidomimetic compounds for biochemical studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	T-Butyl 4-Carboxybenzamide
CAS No.	215118-68-6
Molecular Formula	C12H15NO3
Molecular Weight	221.25 g/mol
Synonyms	4-(tert-Butylcarbamoyl)benzoic acid; 4-Carboxy-N-tert-butylbenzamide; p-Carboxy-N-tert-butylbenzamide; Benzoic acid, 4-[(1,1-dimethylethyl)amino]carbonyl]-; N-tert-Butyl-4-carboxybenzamide; T-Butyl-4-carbamoylbenzoate (common misnomer); 4-(N-tert-Butylaminocarbonyl)benzoic Acid; TBBA (abbreviation)
EINECS	Contact for details

Quality Control

Every batch of T-Butyl 4-Carboxybenzamide is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), is performed. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.