Description

4(3H)-Quinazolinone, 7,8-Dimethoxy-2-Methyl-3-[4-(Phenylmethoxy)Phenyl]- is a high-purity, synthetic organic compound belonging to the quinazolinone class, a scaffold of significant pharmaceutical interest. This compound serves as a critical advanced intermediate or building block in the research and development of novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in drug discovery programs, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties.
• Biochemical Tool Compound: Employed in vitro and in vivo to study specific biological pathways and validate novel therapeutic targets.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.
• Custom Synthesis Building Block: Utilized for the preparation of more complex, proprietary molecules in collaborative drug discovery projects.

Basic Information

Product Name	4(3H)-Quinazolinone, 7,8-Dimethoxy-2-Methyl-3-[4-(Phenylmethoxy)Phenyl]-
CAS No.	214846-04-5
Molecular Formula	C24H22N2O4
Molecular Weight	402.45 g/mol
Synonyms	7,8-Dimethoxy-2-methyl-3-[4-(phenylmethoxy)phenyl]-4(3H)-quinazolinone; 3-[4-(Benzyloxy)phenyl]-7,8-dimethoxy-2-methyl-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 7,8-dimethoxy-2-methyl-3-[4-(phenylmethoxy)phenyl]-; 214846-04-5; 7,8-Dimethoxy-2-methyl-3-(4-benzyloxyphenyl)quinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our 4(3H)-Quinazolinone derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with complete analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light) and should be handled under inert atmosphere if found to be easily oxidized.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area Percent)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.