Description

7-(Benzyloxy)-4-Chloro-6-Methoxyquinoline-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex quinoline-based molecular structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), enabling research and development in targeted therapeutic areas. It is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical suppliers serving the global life sciences industry.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly in oncology and antiviral research.
• Chemical Synthesis Building Block: Used in organic synthesis for constructing quinoline and fused heterocyclic ring systems with specific functionalization.
• Research & Development: Essential for medicinal chemistry programs exploring structure-activity relationships (SAR) of quinoline derivatives.
• API Manufacturing: Employed in the scaled-up production pathways for active pharmaceutical ingredients under controlled GMP environments.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	7-(Benzyloxy)-4-Chloro-6-Methoxyquinoline-3-Carbonitrile
CAS No.	214476-99-0
Molecular Formula	C18H13ClN2O2
Molecular Weight	324.76 g/mol
Synonyms	4-Chloro-7-(phenylmethoxy)-6-methoxy-3-quinolinecarbonitrile; 4-Chloro-6-methoxy-7-(benzyloxy)quinoline-3-carbonitrile; 7-Benzyloxy-4-chloro-6-methoxyquinoline-3-carbonitrile; 3-Cyano-4-chloro-7-benzyloxy-6-methoxyquinoline; Quinoline-3-carbonitrile, 4-chloro-7-(phenylmethoxy)-6-methoxy-; 214476-99-0; 4-Chloro-7-benzyloxy-6-methoxyquinoline-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 7-(Benzyloxy)-4-Chloro-6-Methoxyquinoline-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), related substances, and physical characteristics is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.